Detection of Colorectal Serrated Polyps by Stool DNA Testing: Comparison with Fecal Immunochemical Testing for Occult Blood (FIT)
نویسندگان
چکیده
منابع مشابه
Detection of Colorectal Serrated Polyps by Stool DNA Testing: Comparison with Fecal Immunochemical Testing for Occult Blood (FIT)
OBJECTIVES Precursors to 1/3 of colorectal cancer (CRC), serrated polyps have been under-detected by screening due to their inconspicuous, non-hemorrhagic, and proximal nature. A new multi-target stool DNA test (multi-target sDNA) shows high sensitivity for both CRC and advanced adenomas. Screen detection of serrated polyps by this approach requires further validation. We sought to assess and c...
متن کاملHarms, benefits and costs of fecal immunochemical testing versus guaiac fecal occult blood testing for colorectal cancer screening
BACKGROUND The ColonCancerCheck screening program for colorectal cancer (CRC) in Ontario, Canada, is considering switching from biennial guaiac fecal occult blood test (gFOBT) screening between age 50-74 years to the more sensitive, but also less specific fecal immunochemical test (FIT). The aim of this study is to estimate whether the additional benefits of FIT screening compared to gFOBT outw...
متن کاملScreening for colorectal cancer with fecal occult blood testing.
153 SCREENING FOR COLORECTAL CANCER WITH FECAL OCCULT BLOOD TESTING AND COLONOSCOPY: CORRELATION OF CLINICAL DATA, SITE, SIZE AND DISEASE’S STAGE Iuliana Taraşi, Gabriela Florenţa Dumitrescu, Anca Indrei, P. Plămădeală, Anca Trifan, C. Stanciu, 1 Departament of Gastroenterology, „St. Spiridon” Emergency Clinical Hospital Iaşi 2 Department of Pathology, „Prof. Dr. N. Oblu” Emergency Clinical Hos...
متن کاملFecal occult blood testing for colorectal cancer: a perspective.
Colorectal cancer is an important health problem in western countries. Early detection of colorectal cancer reduces mortality. The best evidence for the effectiveness of screening for colorectal cancer is with annual or biennial fecal occult blood testing. While the benefit of fecal occult blood testing is small in absolute terms, the incremental cost-effectiveness of this screening strategy ap...
متن کاملFecal occult blood testing for colorectal cancer screening.
BACKGROUND Hemoccult II, a widely used guaiac test for fecal occult blood, has a low sensitivity for detecting colorectal neoplasms in asymptomatic patients at average risk. In such patients, the performance characteristics of screening tests developed to improve on Hemoccult II are not known. METHODS A set of three fecal occult-blood tests--Hemoccult II; Hemoccult II Sensa, a more sensitive ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: PLoS ONE
سال: 2014
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0085659